Maternal Humoral Immune Responses Do Not Predict Postnatal HIV-1 Transmission Risk in Antiretroviral-Treated Mothers from the IMPAACT PROMISE Study

Maternal Humoral Immune Responses Do Not Predict Postnatal HIV-1 Transmission Risk in Antiretroviral-Treated Mothers from the IMPAACT PROMISE Study

ABSTRACT To design immune interventions that can synergize with antiretroviral therapy (ART) to reduce the rate of HIV mother-to-child transmission (MTCT), it is essential to characterize maternal immune responses in the setting of ART during pregnancy and breastfeeding and define their effect on MT...

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Bibliographic Details
Main Authors: Eliza D. Hompe, Denise L. Jacobson, Joshua A. Eudailey, Kevin Butler, Whitney Edwards, Justin Pollara, Sean S. Brummel, Genevieve G. Fouda, Lameck Chinula, Melvin Kamanga, Aarti Kinikar, Dhayendre Moodley, Maxensia Owor, Mary Glenn Fowler, Sallie R. Permar
Format: article
Language:EN
Published: American Society for Microbiology 2019
Subjects:
ADCC
HIV-1
antibodies
antiretroviral therapy
breast milk
postnatal transmission
Microbiology
QR1-502
Online Access:https://doaj.org/article/f3118fd17291486192284b83c44373a0
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https://doaj.org/article/f3118fd17291486192284b83c44373a0

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