Nonclonal Emergence of Colistin Resistance Associated with Mutations in the BasRS Two-Component System in <named-content content-type="genus-species">Escherichia coli</named-content> Bloodstream Isolates
ABSTRACT Infections by multidrug-resistant Gram-negative bacteria are increasingly common, prompting the renewed interest in the use of colistin. Colistin specifically targets Gram-negative bacteria by interacting with the anionic lipid A moieties of lipopolysaccharides, leading to membrane destabil...
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| Main Authors: | , , , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
American Society for Microbiology
2020
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| Subjects: | |
| Online Access: | https://doaj.org/article/f3252623321a4b8a8b5cbada519deefc |
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