Semi-supervised prediction of SH2-peptide interactions from imbalanced high-throughput data.

Src homology 2 (SH2) domains are the largest family of the peptide-recognition modules (PRMs) that bind to phosphotyrosine containing peptides. Knowledge about binding partners of SH2-domains is key for a deeper understanding of different cellular processes. Given the high binding specificity of SH2...

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Autores principales: Kousik Kundu, Fabrizio Costa, Michael Huber, Michael Reth, Rolf Backofen
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/f35489c5c55e4b639f9e07db970d9c99
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