Semi-supervised prediction of SH2-peptide interactions from imbalanced high-throughput data.
Src homology 2 (SH2) domains are the largest family of the peptide-recognition modules (PRMs) that bind to phosphotyrosine containing peptides. Knowledge about binding partners of SH2-domains is key for a deeper understanding of different cellular processes. Given the high binding specificity of SH2...
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Main Authors: | Kousik Kundu, Fabrizio Costa, Michael Huber, Michael Reth, Rolf Backofen |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2013
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Online Access: | https://doaj.org/article/f35489c5c55e4b639f9e07db970d9c99 |
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