A model of DNA damage response activation at stalled replication forks by SPRTN

The process of DNA replication is threatened by many factors, including DNA lesions, and machineries acting as obstacles. Here we discuss and speculate on a recently proposed mechanism of DNA damage response activation in response to lesions that challenge the progression of DNA replication forks.

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Detalles Bibliográficos
Autores principales:	Christopher Bruhn, Marco Foiani
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f367c6151ba84697a0a594a8dd42fb3f
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spelling	oai:doaj.org-article:f367c6151ba84697a0a594a8dd42fb3f2021-12-02T16:57:42ZA model of DNA damage response activation at stalled replication forks by SPRTN10.1038/s41467-019-13610-72041-1723https://doaj.org/article/f367c6151ba84697a0a594a8dd42fb3f2019-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13610-7https://doaj.org/toc/2041-1723The process of DNA replication is threatened by many factors, including DNA lesions, and machineries acting as obstacles. Here we discuss and speculate on a recently proposed mechanism of DNA damage response activation in response to lesions that challenge the progression of DNA replication forks.Christopher BruhnMarco FoianiNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-3 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Christopher Bruhn Marco Foiani A model of DNA damage response activation at stalled replication forks by SPRTN
description	The process of DNA replication is threatened by many factors, including DNA lesions, and machineries acting as obstacles. Here we discuss and speculate on a recently proposed mechanism of DNA damage response activation in response to lesions that challenge the progression of DNA replication forks.
format	article
author	Christopher Bruhn Marco Foiani
author_facet	Christopher Bruhn Marco Foiani
author_sort	Christopher Bruhn
title	A model of DNA damage response activation at stalled replication forks by SPRTN
title_short	A model of DNA damage response activation at stalled replication forks by SPRTN
title_full	A model of DNA damage response activation at stalled replication forks by SPRTN
title_fullStr	A model of DNA damage response activation at stalled replication forks by SPRTN
title_full_unstemmed	A model of DNA damage response activation at stalled replication forks by SPRTN
title_sort	model of dna damage response activation at stalled replication forks by sprtn
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/f367c6151ba84697a0a594a8dd42fb3f
work_keys_str_mv	AT christopherbruhn amodelofdnadamageresponseactivationatstalledreplicationforksbysprtn AT marcofoiani amodelofdnadamageresponseactivationatstalledreplicationforksbysprtn AT christopherbruhn modelofdnadamageresponseactivationatstalledreplicationforksbysprtn AT marcofoiani modelofdnadamageresponseactivationatstalledreplicationforksbysprtn
_version_	1718382540462489600

A model of DNA damage response activation at stalled replication forks by SPRTN

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