Integrative effect of carvedilol and aerobic exercise training therapies on improving cardiac contractility and remodeling in heart failure mice.

The use of β-blockers is mandatory for counteracting heart failure (HF)-induced chronic sympathetic hyperactivity, cardiac dysfunction and remodeling. Importantly, aerobic exercise training, an efficient nonpharmacological therapy to HF, also counteracts sympathetic hyperactivity in HF and improves...

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Autores principales: Andréa S Vanzelli, Alessandra Medeiros, Natale Rolim, Jan B Bartholomeu, Telma F Cunha, Luiz R G Bechara, Enéas R M Gomes, Katt C Mattos, Raquel Sirvente, Vera Maria Cury Salemi, Charles Mady, Carlos E Negrao, Silvia Guatimosim, Patricia C Brum
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/f3a4035ed3334823abfd5dbb073bd531
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