Helminth-induced IL-4 expands bystander memory CD8 + T cells for early control of viral infection

Parasitic helminth infection is known to impact upon the host response to other bystander inflammatory processes. Here the authors show that IL4 production induced by helminth infection results in expansion of bystander CD8+ memory T cells and enhanced control to viral infection.

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Autores principales:	Marion Rolot, Annette M. Dougall, Alisha Chetty, Justine Javaux, Ting Chen, Xue Xiao, Bénédicte Machiels, Murray E. Selkirk, Rick M. Maizels, Cornelis Hokke, Olivier Denis, Frank Brombacher, Alain Vanderplasschen, Laurent Gillet, William G. C. Horsnell, Benjamin G. Dewals
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f3ad242413cc462394be270aad7af477
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spelling	oai:doaj.org-article:f3ad242413cc462394be270aad7af4772021-12-02T17:33:03ZHelminth-induced IL-4 expands bystander memory CD8 + T cells for early control of viral infection10.1038/s41467-018-06978-52041-1723https://doaj.org/article/f3ad242413cc462394be270aad7af4772018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06978-5https://doaj.org/toc/2041-1723Parasitic helminth infection is known to impact upon the host response to other bystander inflammatory processes. Here the authors show that IL4 production induced by helminth infection results in expansion of bystander CD8+ memory T cells and enhanced control to viral infection.Marion RolotAnnette M. DougallAlisha ChettyJustine JavauxTing ChenXue XiaoBénédicte MachielsMurray E. SelkirkRick M. MaizelsCornelis HokkeOlivier DenisFrank BrombacherAlain VanderplasschenLaurent GilletWilliam G. C. HorsnellBenjamin G. DewalsNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Marion Rolot Annette M. Dougall Alisha Chetty Justine Javaux Ting Chen Xue Xiao Bénédicte Machiels Murray E. Selkirk Rick M. Maizels Cornelis Hokke Olivier Denis Frank Brombacher Alain Vanderplasschen Laurent Gillet William G. C. Horsnell Benjamin G. Dewals Helminth-induced IL-4 expands bystander memory CD8 + T cells for early control of viral infection
description	Parasitic helminth infection is known to impact upon the host response to other bystander inflammatory processes. Here the authors show that IL4 production induced by helminth infection results in expansion of bystander CD8+ memory T cells and enhanced control to viral infection.
format	article
author	Marion Rolot Annette M. Dougall Alisha Chetty Justine Javaux Ting Chen Xue Xiao Bénédicte Machiels Murray E. Selkirk Rick M. Maizels Cornelis Hokke Olivier Denis Frank Brombacher Alain Vanderplasschen Laurent Gillet William G. C. Horsnell Benjamin G. Dewals
author_facet	Marion Rolot Annette M. Dougall Alisha Chetty Justine Javaux Ting Chen Xue Xiao Bénédicte Machiels Murray E. Selkirk Rick M. Maizels Cornelis Hokke Olivier Denis Frank Brombacher Alain Vanderplasschen Laurent Gillet William G. C. Horsnell Benjamin G. Dewals
author_sort	Marion Rolot
title	Helminth-induced IL-4 expands bystander memory CD8 + T cells for early control of viral infection
title_short	Helminth-induced IL-4 expands bystander memory CD8 + T cells for early control of viral infection
title_full	Helminth-induced IL-4 expands bystander memory CD8 + T cells for early control of viral infection
title_fullStr	Helminth-induced IL-4 expands bystander memory CD8 + T cells for early control of viral infection
title_full_unstemmed	Helminth-induced IL-4 expands bystander memory CD8 + T cells for early control of viral infection
title_sort	helminth-induced il-4 expands bystander memory cd8 + t cells for early control of viral infection
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/f3ad242413cc462394be270aad7af477
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Helminth-induced IL-4 expands bystander memory CD8 + T cells for early control of viral infection

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