Helminth-induced IL-4 expands bystander memory CD8 + T cells for early control of viral infection

Helminth-induced IL-4 expands bystander memory CD8 + T cells for early control of viral infection

Parasitic helminth infection is known to impact upon the host response to other bystander inflammatory processes. Here the authors show that IL4 production induced by helminth infection results in expansion of bystander CD8+ memory T cells and enhanced control to viral infection.

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Detalles Bibliográficos
Autores principales: Marion Rolot, Annette M. Dougall, Alisha Chetty, Justine Javaux, Ting Chen, Xue Xiao, Bénédicte Machiels, Murray E. Selkirk, Rick M. Maizels, Cornelis Hokke, Olivier Denis, Frank Brombacher, Alain Vanderplasschen, Laurent Gillet, William G. C. Horsnell, Benjamin G. Dewals
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Science
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Acceso en línea:https://doaj.org/article/f3ad242413cc462394be270aad7af477
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Internet

https://doaj.org/article/f3ad242413cc462394be270aad7af477

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