Receptor depletion and recovery in small-intestinal neuroendocrine tumors and normal tissues after administration of a single intravenous dose of octreotide measured by 68Ga-DOTATOC PET/CT
Abstract Background Low-grade neuroendocrine tumors (NETs) are characterized by an abundance of somatostatin receptors (SSTR) that can be targeted with somatostatin analogs (SSA). When activated with a single dose of SSA, the receptor-ligand complex is internalized, and the receptor is by default re...
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Main Authors: | Ulrika Jahn, Ezgi Ilan, Irina Velikyan, Katarzyna Fröss-Baron, Mark Lubberink, Anders Sundin |
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Format: | article |
Language: | EN |
Published: |
SpringerOpen
2021
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Online Access: | https://doaj.org/article/f3e995fbfe0340859a0afc0a75e0b79b |
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