Impact of malnourishment on the pharmacokinetics of acetaminophen and susceptibility to acetaminophen hepatotoxicity

Abstract Background Acetaminophen hepatotoxicity is thought to be primarily caused by formation of the specific reactive metabolite N‐acetyl‐para‐benzo‐quinone imine (NAPQI). Malnourished individuals are at increased risk of acetaminophen‐related hepatotoxicity. We report a case of low acetaminophen...

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Autores principales: Daan Zillen, Kris L. L. Movig, Gert Kant, Joost B. Masselink, Paola Mian
Formato: article
Lenguaje:EN
Publicado: Wiley 2021
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R
Acceso en línea:https://doaj.org/article/f3eaae8c5ba54ab6988fb92bf2126695
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