Nerve Growth Factor (NGF) modulates in vitro induced myofibroblasts by highlighting a differential protein signature

Abstract We previously described the profibrogenic effect of NGF on conjunctival Fibroblasts (FBs) and its ability to trigger apoptosis in TGFβ1-induced myofibroblasts (myoFBs). Herein, cell apoptosis/signalling, cytokines’ signature in conditioned media and inflammatory as well as angiogenic pathwa...

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Autores principales: Graziana Esposito, Bijorn Omar Balzamino, Egidio Stigliano, Filippo Biamonte, Andrea Urbani, Alessandra Micera
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/f3f8d4a5e47740d4ab769020c370618d
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