Elongin B-Mediated Epigenetic Alteration of Viral Chromatin Correlates with Efficient Human Cytomegalovirus Gene Expression and Replication
ABSTRACT Elongins B and C are members of complexes that increase the efficiency of transcriptional elongation by RNA polymerase II (RNAPII) and enhance the monoubiquitination of histone H2B, an epigenetic mark of actively transcribed genes. Here we show that, in addition to its role in facilitating...
Enregistré dans:
Auteurs principaux: | Jiwon Hwang, Ryan T. Saffert, Robert F. Kalejta |
---|---|
Format: | article |
Langue: | EN |
Publié: |
American Society for Microbiology
2011
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/f40ccdd11f904dafb4531c88bda7b46b |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Polycomb repressive complex 2 targets murine cytomegalovirus chromatin for modification and associates with viral replication centers.
par: Christopher G Abraham, et autres
Publié: (2012) -
Human Cytomegalovirus Genomes Survive Mitosis via the IE19 Chromatin-Tethering Domain
par: Shelby M. Lyon, et autres
Publié: (2020) -
Human cytomegalovirus-induced host protein citrullination is crucial for viral replication
par: Gloria Griffante, et autres
Publié: (2021) - Epigenetics & chromatin
-
A human cytomegalovirus-encoded microRNA regulates expression of multiple viral genes involved in replication.
par: Finn Grey, et autres
Publié: (2007)