Elongin B-Mediated Epigenetic Alteration of Viral Chromatin Correlates with Efficient Human Cytomegalovirus Gene Expression and Replication

ABSTRACT Elongins B and C are members of complexes that increase the efficiency of transcriptional elongation by RNA polymerase II (RNAPII) and enhance the monoubiquitination of histone H2B, an epigenetic mark of actively transcribed genes. Here we show that, in addition to its role in facilitating...

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Auteurs principaux: Jiwon Hwang, Ryan T. Saffert, Robert F. Kalejta
Format: article
Langue:EN
Publié: American Society for Microbiology 2011
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Accès en ligne:https://doaj.org/article/f40ccdd11f904dafb4531c88bda7b46b
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