Elongin B-Mediated Epigenetic Alteration of Viral Chromatin Correlates with Efficient Human Cytomegalovirus Gene Expression and Replication

ABSTRACT Elongins B and C are members of complexes that increase the efficiency of transcriptional elongation by RNA polymerase II (RNAPII) and enhance the monoubiquitination of histone H2B, an epigenetic mark of actively transcribed genes. Here we show that, in addition to its role in facilitating...

Full description

Saved in:
Bibliographic Details
Main Authors: Jiwon Hwang, Ryan T. Saffert, Robert F. Kalejta
Format: article
Language:EN
Published: American Society for Microbiology 2011
Subjects:
Online Access:https://doaj.org/article/f40ccdd11f904dafb4531c88bda7b46b
Tags: Add Tag
No Tags, Be the first to tag this record!