The Hippo pathway regulates density-dependent proliferation of iPSC-derived cardiac myocytes

Abstract Inducing cardiac myocytes to proliferate is considered a potential therapy to target heart disease, however, modulating cardiac myocyte proliferation has proven to be a technical challenge. The Hippo pathway is a kinase signaling cascade that regulates cell proliferation during the growth o...

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Autores principales: Abigail C. Neininger, Xiaozhaun Dai, Qi Liu, Dylan T. Burnette
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/f4155b51a5fa464eaa907c1d55a99b40
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