Novel method to load multiple genes onto a mammalian artificial chromosome.
Mammalian artificial chromosomes are natural chromosome-based vectors that may carry a vast amount of genetic material in terms of both size and number. They are reasonably stable and segregate well in both mitosis and meiosis. A platform artificial chromosome expression system (ACEs) was earlier de...
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Main Authors: | Anna Tóth, Katalin Fodor, Tünde Praznovszky, Vilmos Tubak, Andor Udvardy, Gyula Hadlaczky, Robert L Katona |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2014
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Subjects: | |
Online Access: | https://doaj.org/article/f4273f10e4a3495b9e5d460d1935b20b |
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