Novel method to load multiple genes onto a mammalian artificial chromosome.

Mammalian artificial chromosomes are natural chromosome-based vectors that may carry a vast amount of genetic material in terms of both size and number. They are reasonably stable and segregate well in both mitosis and meiosis. A platform artificial chromosome expression system (ACEs) was earlier de...

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Auteurs principaux: Anna Tóth, Katalin Fodor, Tünde Praznovszky, Vilmos Tubak, Andor Udvardy, Gyula Hadlaczky, Robert L Katona
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2014
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Accès en ligne:https://doaj.org/article/f4273f10e4a3495b9e5d460d1935b20b
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