Prior vaccination with rVSV-ZEBOV does not interfere with but improves efficacy of postexposure antibody treatment

During an ongoing Ebola virus outbreak, infection before onset of protective immunity from vaccination is a possible scenario. Here the authors show in non-human primates that vaccination shortly before treatment with a monoclonal antibody does not negatively affect effectiveness of the antibody the...

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Autores principales:	Robert W. Cross, Zachary A. Bornholdt, Abhishek N. Prasad, Joan B. Geisbert, Viktoriya Borisevich, Krystle N. Agans, Daniel J. Deer, Kevin Melody, Karla A. Fenton, Heinz Feldmann, Armand Sprecher, Larry Zeitlin, Thomas W. Geisbert
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f42ceaff066b4e269cda66de8d4403a1
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spelling	oai:doaj.org-article:f42ceaff066b4e269cda66de8d4403a12021-12-02T16:14:05ZPrior vaccination with rVSV-ZEBOV does not interfere with but improves efficacy of postexposure antibody treatment10.1038/s41467-020-17446-42041-1723https://doaj.org/article/f42ceaff066b4e269cda66de8d4403a12020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17446-4https://doaj.org/toc/2041-1723During an ongoing Ebola virus outbreak, infection before onset of protective immunity from vaccination is a possible scenario. Here the authors show in non-human primates that vaccination shortly before treatment with a monoclonal antibody does not negatively affect effectiveness of the antibody therapy.Robert W. CrossZachary A. BornholdtAbhishek N. PrasadJoan B. GeisbertViktoriya BorisevichKrystle N. AgansDaniel J. DeerKevin MelodyKarla A. FentonHeinz FeldmannArmand SprecherLarry ZeitlinThomas W. GeisbertNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Robert W. Cross Zachary A. Bornholdt Abhishek N. Prasad Joan B. Geisbert Viktoriya Borisevich Krystle N. Agans Daniel J. Deer Kevin Melody Karla A. Fenton Heinz Feldmann Armand Sprecher Larry Zeitlin Thomas W. Geisbert Prior vaccination with rVSV-ZEBOV does not interfere with but improves efficacy of postexposure antibody treatment
description	During an ongoing Ebola virus outbreak, infection before onset of protective immunity from vaccination is a possible scenario. Here the authors show in non-human primates that vaccination shortly before treatment with a monoclonal antibody does not negatively affect effectiveness of the antibody therapy.
format	article
author	Robert W. Cross Zachary A. Bornholdt Abhishek N. Prasad Joan B. Geisbert Viktoriya Borisevich Krystle N. Agans Daniel J. Deer Kevin Melody Karla A. Fenton Heinz Feldmann Armand Sprecher Larry Zeitlin Thomas W. Geisbert
author_facet	Robert W. Cross Zachary A. Bornholdt Abhishek N. Prasad Joan B. Geisbert Viktoriya Borisevich Krystle N. Agans Daniel J. Deer Kevin Melody Karla A. Fenton Heinz Feldmann Armand Sprecher Larry Zeitlin Thomas W. Geisbert
author_sort	Robert W. Cross
title	Prior vaccination with rVSV-ZEBOV does not interfere with but improves efficacy of postexposure antibody treatment
title_short	Prior vaccination with rVSV-ZEBOV does not interfere with but improves efficacy of postexposure antibody treatment
title_full	Prior vaccination with rVSV-ZEBOV does not interfere with but improves efficacy of postexposure antibody treatment
title_fullStr	Prior vaccination with rVSV-ZEBOV does not interfere with but improves efficacy of postexposure antibody treatment
title_full_unstemmed	Prior vaccination with rVSV-ZEBOV does not interfere with but improves efficacy of postexposure antibody treatment
title_sort	prior vaccination with rvsv-zebov does not interfere with but improves efficacy of postexposure antibody treatment
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/f42ceaff066b4e269cda66de8d4403a1
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Prior vaccination with rVSV-ZEBOV does not interfere with but improves efficacy of postexposure antibody treatment

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