AIP1 and cofilin ensure a resistance to tissue tension and promote directional cell rearrangement

Cells must resist or release tension/compression when proliferating and moving during development. Here the authors show that AIP1, together with cofilin, promotes local actin turnover to regulate linkage between actomyosin and cell junctions and resist mechanical load imposed by tissue stretching.

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Autores principales: Keisuke Ikawa, Kaoru Sugimura
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Q
Acceso en línea:https://doaj.org/article/f43c110b43a2482980078f5eb2c01046
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