AIP1 and cofilin ensure a resistance to tissue tension and promote directional cell rearrangement
Cells must resist or release tension/compression when proliferating and moving during development. Here the authors show that AIP1, together with cofilin, promotes local actin turnover to regulate linkage between actomyosin and cell junctions and resist mechanical load imposed by tissue stretching.
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Nature Portfolio
2018
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oai:doaj.org-article:f43c110b43a2482980078f5eb2c010462021-12-02T15:33:38ZAIP1 and cofilin ensure a resistance to tissue tension and promote directional cell rearrangement10.1038/s41467-018-05605-72041-1723https://doaj.org/article/f43c110b43a2482980078f5eb2c010462018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05605-7https://doaj.org/toc/2041-1723Cells must resist or release tension/compression when proliferating and moving during development. Here the authors show that AIP1, together with cofilin, promotes local actin turnover to regulate linkage between actomyosin and cell junctions and resist mechanical load imposed by tissue stretching.Keisuke IkawaKaoru SugimuraNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018) |
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Science Q Keisuke Ikawa Kaoru Sugimura AIP1 and cofilin ensure a resistance to tissue tension and promote directional cell rearrangement |
description |
Cells must resist or release tension/compression when proliferating and moving during development. Here the authors show that AIP1, together with cofilin, promotes local actin turnover to regulate linkage between actomyosin and cell junctions and resist mechanical load imposed by tissue stretching. |
format |
article |
author |
Keisuke Ikawa Kaoru Sugimura |
author_facet |
Keisuke Ikawa Kaoru Sugimura |
author_sort |
Keisuke Ikawa |
title |
AIP1 and cofilin ensure a resistance to tissue tension and promote directional cell rearrangement |
title_short |
AIP1 and cofilin ensure a resistance to tissue tension and promote directional cell rearrangement |
title_full |
AIP1 and cofilin ensure a resistance to tissue tension and promote directional cell rearrangement |
title_fullStr |
AIP1 and cofilin ensure a resistance to tissue tension and promote directional cell rearrangement |
title_full_unstemmed |
AIP1 and cofilin ensure a resistance to tissue tension and promote directional cell rearrangement |
title_sort |
aip1 and cofilin ensure a resistance to tissue tension and promote directional cell rearrangement |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/f43c110b43a2482980078f5eb2c01046 |
work_keys_str_mv |
AT keisukeikawa aip1andcofilinensurearesistancetotissuetensionandpromotedirectionalcellrearrangement AT kaorusugimura aip1andcofilinensurearesistancetotissuetensionandpromotedirectionalcellrearrangement |
_version_ |
1718387059876429824 |