AIP1 and cofilin ensure a resistance to tissue tension and promote directional cell rearrangement

Cells must resist or release tension/compression when proliferating and moving during development. Here the authors show that AIP1, together with cofilin, promotes local actin turnover to regulate linkage between actomyosin and cell junctions and resist mechanical load imposed by tissue stretching.

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Autores principales: Keisuke Ikawa, Kaoru Sugimura
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/f43c110b43a2482980078f5eb2c01046
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spelling oai:doaj.org-article:f43c110b43a2482980078f5eb2c010462021-12-02T15:33:38ZAIP1 and cofilin ensure a resistance to tissue tension and promote directional cell rearrangement10.1038/s41467-018-05605-72041-1723https://doaj.org/article/f43c110b43a2482980078f5eb2c010462018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05605-7https://doaj.org/toc/2041-1723Cells must resist or release tension/compression when proliferating and moving during development. Here the authors show that AIP1, together with cofilin, promotes local actin turnover to regulate linkage between actomyosin and cell junctions and resist mechanical load imposed by tissue stretching.Keisuke IkawaKaoru SugimuraNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Keisuke Ikawa
Kaoru Sugimura
AIP1 and cofilin ensure a resistance to tissue tension and promote directional cell rearrangement
description Cells must resist or release tension/compression when proliferating and moving during development. Here the authors show that AIP1, together with cofilin, promotes local actin turnover to regulate linkage between actomyosin and cell junctions and resist mechanical load imposed by tissue stretching.
format article
author Keisuke Ikawa
Kaoru Sugimura
author_facet Keisuke Ikawa
Kaoru Sugimura
author_sort Keisuke Ikawa
title AIP1 and cofilin ensure a resistance to tissue tension and promote directional cell rearrangement
title_short AIP1 and cofilin ensure a resistance to tissue tension and promote directional cell rearrangement
title_full AIP1 and cofilin ensure a resistance to tissue tension and promote directional cell rearrangement
title_fullStr AIP1 and cofilin ensure a resistance to tissue tension and promote directional cell rearrangement
title_full_unstemmed AIP1 and cofilin ensure a resistance to tissue tension and promote directional cell rearrangement
title_sort aip1 and cofilin ensure a resistance to tissue tension and promote directional cell rearrangement
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/f43c110b43a2482980078f5eb2c01046
work_keys_str_mv AT keisukeikawa aip1andcofilinensurearesistancetotissuetensionandpromotedirectionalcellrearrangement
AT kaorusugimura aip1andcofilinensurearesistancetotissuetensionandpromotedirectionalcellrearrangement
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