AIP1 and cofilin ensure a resistance to tissue tension and promote directional cell rearrangement

Cells must resist or release tension/compression when proliferating and moving during development. Here the authors show that AIP1, together with cofilin, promotes local actin turnover to regulate linkage between actomyosin and cell junctions and resist mechanical load imposed by tissue stretching.

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Main Authors:	Keisuke Ikawa, Kaoru Sugimura
Format:	article
Language:	EN
Published:	Nature Portfolio 2018
Subjects:	Science Q
Online Access:	https://doaj.org/article/f43c110b43a2482980078f5eb2c01046
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spelling	oai:doaj.org-article:f43c110b43a2482980078f5eb2c010462021-12-02T15:33:38ZAIP1 and cofilin ensure a resistance to tissue tension and promote directional cell rearrangement10.1038/s41467-018-05605-72041-1723https://doaj.org/article/f43c110b43a2482980078f5eb2c010462018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05605-7https://doaj.org/toc/2041-1723Cells must resist or release tension/compression when proliferating and moving during development. Here the authors show that AIP1, together with cofilin, promotes local actin turnover to regulate linkage between actomyosin and cell junctions and resist mechanical load imposed by tissue stretching.Keisuke IkawaKaoru SugimuraNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Keisuke Ikawa Kaoru Sugimura AIP1 and cofilin ensure a resistance to tissue tension and promote directional cell rearrangement
description	Cells must resist or release tension/compression when proliferating and moving during development. Here the authors show that AIP1, together with cofilin, promotes local actin turnover to regulate linkage between actomyosin and cell junctions and resist mechanical load imposed by tissue stretching.
format	article
author	Keisuke Ikawa Kaoru Sugimura
author_facet	Keisuke Ikawa Kaoru Sugimura
author_sort	Keisuke Ikawa
title	AIP1 and cofilin ensure a resistance to tissue tension and promote directional cell rearrangement
title_short	AIP1 and cofilin ensure a resistance to tissue tension and promote directional cell rearrangement
title_full	AIP1 and cofilin ensure a resistance to tissue tension and promote directional cell rearrangement
title_fullStr	AIP1 and cofilin ensure a resistance to tissue tension and promote directional cell rearrangement
title_full_unstemmed	AIP1 and cofilin ensure a resistance to tissue tension and promote directional cell rearrangement
title_sort	aip1 and cofilin ensure a resistance to tissue tension and promote directional cell rearrangement
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/f43c110b43a2482980078f5eb2c01046
work_keys_str_mv	AT keisukeikawa aip1andcofilinensurearesistancetotissuetensionandpromotedirectionalcellrearrangement AT kaorusugimura aip1andcofilinensurearesistancetotissuetensionandpromotedirectionalcellrearrangement
_version_	1718387059876429824

AIP1 and cofilin ensure a resistance to tissue tension and promote directional cell rearrangement

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