Collagen-producing lung cell atlas identifies multiple subsets with distinct localization and relevance to fibrosis

Collagen-producing lung cell atlas identifies multiple subsets with distinct localization and relevance to fibrosis

Collagen production by lung cells is critical to maintain organ architecture but can also drive pathological scarring. Here the authors perform single cell RNA sequencing of collagen-producing lung cells identifying a subset of pathologic fibroblasts characterized by Cthrc1 expression which are conc...

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Main Authors: Tatsuya Tsukui, Kai-Hui Sun, Joseph B. Wetter, John R. Wilson-Kanamori, Lisa A. Hazelwood, Neil C. Henderson, Taylor S. Adams, Jonas C. Schupp, Sergio D. Poli, Ivan O. Rosas, Naftali Kaminski, Michael A. Matthay, Paul J. Wolters, Dean Sheppard
Format: article
Language:EN
Published: Nature Portfolio 2020
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Science
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Online Access:https://doaj.org/article/f45292590a314d048725872415c1b587
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https://doaj.org/article/f45292590a314d048725872415c1b587

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