DOR/Tp53inp2 and Tp53inp1 constitute a metazoan gene family encoding dual regulators of autophagy and transcription.

DOR/Tp53inp2 and Tp53inp1 constitute a metazoan gene family encoding dual regulators of autophagy and transcription.

Human DOR/TP53INP2 displays a unique bifunctional role as a modulator of autophagy and gene transcription. However, the domains or regions of DOR that participate in those functions have not been identified. Here we have performed structure/function analyses of DOR guided by identification of conser...

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Autores principales: Ana Sancho, Jordi Duran, Antonio García-España, Caroline Mauvezin, Endalkachew A Alemu, Trond Lamark, Maria J Macias, Rob DeSalle, Miriam Royo, David Sala, Javier U Chicote, Manuel Palacín, Terje Johansen, Antonio Zorzano
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
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Science
Q
Acceso en línea:https://doaj.org/article/f4592fb024084229acac77dc5f3623ca
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https://doaj.org/article/f4592fb024084229acac77dc5f3623ca

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