Non-blocking modulation contributes to sodium channel inhibition by a covalently attached photoreactive riluzole analog
Abstract Sodium channel inhibitor drugs decrease pathological hyperactivity in various diseases including pain syndromes, myotonia, arrhythmias, nerve injuries and epilepsies. Inhibiting pathological but not physiological activity, however, is a major challenge in drug development. Sodium channel in...
Guardado en:
Autores principales: | Peter Lukacs, Mátyás C. Földi, Luca Valánszki, Emilio Casanova, Beáta Biri-Kovács, László Nyitray, András Málnási-Csizmadia, Arpad Mike |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
|
Materias: | |
Acceso en línea: | https://doaj.org/article/f48d2435c9aa4403b15cfc5aca00707f |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Visible light-photoreactive composite surfaces with thermoresponsive wetting and photocatalytic properties
por: László Mérai, et al.
Publicado: (2022) -
Adherence to riluzole in patients with amyotrophic lateral sclerosis: an observational study
por: Introna A, et al.
Publicado: (2018) -
In silico studies reveal structural deviations of mutant profilin-1 and interaction with riluzole and edaravone in amyotrophic lateral sclerosis
por: Ahmad Shahir Sadr, et al.
Publicado: (2021) -
Radiative analysis of luminescence in photoreactive systems: Application to photosensitizers for solar fuel production.
por: Caroline Supplis, et al.
Publicado: (2021) -
Photoreactivity of an Exemplary Anthracene Mixture Revealed by NMR Studies, including a Kinetic Approach
por: Kristina Kristinaityte, et al.
Publicado: (2021)