ORMDL3 overexpression facilitates FcεRI‐mediated transcription of proinflammatory cytokines and thapsigargin‐mediated PERK phosphorylation in RBL‐2H3 cells

Abstract Introduction The chromosomal region 17q21 harbors the human orosomucoid‐like 3 (ORMDL3) gene and has been linked to asthma and other inflammatory diseases. ORMDL3 is involved in the unfolded protein response (UPR), lipid metabolism, and inflammatory reactions. We investigated the effects of...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Kazuhiro Ogi, Tetsuji Takabayashi, Kaori Tomita, Masafumi Sakashita, Taiyo Morikawa, Takahiro Ninomiya, Masayuki Okamoto, Norihiko Narita, Shigeharu Fujieda
Formato: article
Lenguaje:EN
Publicado: Wiley 2021
Materias:
S1P
UPR
Acceso en línea:https://doaj.org/article/f4a842e6381e47be82ec6d11a0cb3037
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!