Randomized quantile residuals for diagnosing zero-inflated generalized linear mixed models with applications to microbiome count data

Abstract Background For differential abundance analysis, zero-inflated generalized linear models, typically zero-inflated NB models, have been increasingly used to model microbiome and other sequencing count data. A common assumption in estimating the false discovery rate is that the p values are un...

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Bibliographic Details
Main Authors: Wei Bai, Mei Dong, Longhai Li, Cindy Feng, Wei Xu
Format: article
Language:EN
Published: BMC 2021
Subjects:
Online Access:https://doaj.org/article/f4aa6b907cfa402ea9f39d22418ec6df
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