Differential role of SIRT1/MAPK pathway during cerebral ischemia in rats and humans

Abstract Cerebral ischemia (CI) is a severe cause of neurological dysfunction and mortality. Sirtuin-1 (Silent information regulator family protein 1, SIRT1), an oxidized nicotinamide adenine dinucleotide (NAD+)-dependent protein deacetylase, plays an important role in protection against several neu...

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Autores principales: Sireesh Kumar Teertam, Phanithi Prakash Babu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/f4c6e908be314ea6855650e011e52300
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