AID/APOBEC-like cytidine deaminases are ancient innate immune mediators in invertebrates

The AID/APOBEC cytidine deaminase family are nucleic acid editors, important for antigen receptor expression and thought to have evolved along with vertebrate adaptive immunity. Here the authors show this family may have evolved prior to adaptive immunity as members with cytidine deaminase activity...

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Autores principales: Mei-Chen Liu, Wen-Yun Liao, Katherine M. Buckley, Shu Yuan Yang, Jonathan P. Rast, Sebastian D. Fugmann
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/f4d7dc11f8f14ef7b2e471f8328fae2d
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