AID/APOBEC-like cytidine deaminases are ancient innate immune mediators in invertebrates
The AID/APOBEC cytidine deaminase family are nucleic acid editors, important for antigen receptor expression and thought to have evolved along with vertebrate adaptive immunity. Here the authors show this family may have evolved prior to adaptive immunity as members with cytidine deaminase activity...
Guardado en:
Autores principales: | Mei-Chen Liu, Wen-Yun Liao, Katherine M. Buckley, Shu Yuan Yang, Jonathan P. Rast, Sebastian D. Fugmann |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
|
Materias: | |
Acceso en línea: | https://doaj.org/article/f4d7dc11f8f14ef7b2e471f8328fae2d |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Deaminase-independent inhibition of parvoviruses by the APOBEC3A cytidine deaminase.
por: Iñigo Narvaiza, et al.
Publicado: (2009) -
Sustained high expression of multiple APOBEC3 cytidine deaminases in systemic lupus erythematosus
por: Danielle Perez-Bercoff, et al.
Publicado: (2021) -
Expanding C–T base editing toolkit with diversified cytidine deaminases
por: Tian-Lin Cheng, et al.
Publicado: (2019) -
Activation-induced cytidine deaminase alters the subcellular localization of Tet family proteins.
por: Yuko Arioka, et al.
Publicado: (2012) -
Dimerization regulates both deaminase-dependent and deaminase-independent HIV-1 restriction by APOBEC3G
por: Michael Morse, et al.
Publicado: (2017)