AID/APOBEC-like cytidine deaminases are ancient innate immune mediators in invertebrates

The AID/APOBEC cytidine deaminase family are nucleic acid editors, important for antigen receptor expression and thought to have evolved along with vertebrate adaptive immunity. Here the authors show this family may have evolved prior to adaptive immunity as members with cytidine deaminase activity...

Full description

Saved in:
Bibliographic Details
Main Authors: Mei-Chen Liu, Wen-Yun Liao, Katherine M. Buckley, Shu Yuan Yang, Jonathan P. Rast, Sebastian D. Fugmann
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
Q
Online Access:https://doaj.org/article/f4d7dc11f8f14ef7b2e471f8328fae2d
Tags: Add Tag
No Tags, Be the first to tag this record!