Selective Inhibitor of the c-Met Receptor Tyrosine Kinase in Advanced Hepatocellular Carcinoma: No Beneficial Effect With the Use of Tivantinib?

Advanced hepatocellular carcinoma (HCC) remains a formidable health challenge worldwide, with a 5-year survival rate of 2.4% in patients with distant metastases. The hepatocyte growth factor/cellular-mesenchymal-epithelial transition (HGF/c-Met) signaling pathway represents an encouraging therapeuti...

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Bibliographic Details
Main Authors: Shankun Zhao, Weizhou Wu, Hao Jiang, Lei Ma, Chengyi Pan, Chong Jin, Jinggang Mo, Liezhi Wang, Kunpeng Wang
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
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Online Access:https://doaj.org/article/f4e0d617edab4fcba36128a345c3c5df
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