Mechanochemical synthesis of magnesium-based carbon nucleophiles in air and their use in organic synthesis

Grignard reagents have widespread utility in organic chemistry, but their preparation is limited by several drawbacks, such as the use of dry organic solvents and long reaction times. Here, the authors report a general mechanochemical synthesis of Grignard reagents in paste form in air, using a ball...

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Bibliographic Details
Main Authors: Rina Takahashi, Anqi Hu, Pan Gao, Yunpeng Gao, Yadong Pang, Tamae Seo, Julong Jiang, Satoshi Maeda, Hikaru Takaya, Koji Kubota, Hajime Ito
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/f50eccced71c431a8dfbdf97738db055
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