Glucocorticoid receptor wields chromatin interactions to tune transcription for cytoskeleton stabilization in podocytes

Wang et al. use several genome-wide approaches to investigate glucocorticoid receptor (GR) action in a podocyte cell line model. They conclude that direct GR bindings are enriched at super enhancers, highlighting a strategy potentially used by GR to regulate transcription through super-enhancers and...

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Autores principales: Hong Wang, Aiping Duan, Jing Zhang, Qi Wang, Yuexian Xing, Zhaohui Qin, Zhihong Liu, Jingping Yang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/f5148a3c1b8044cdae070252e4de0c16
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