Glucocorticoid receptor wields chromatin interactions to tune transcription for cytoskeleton stabilization in podocytes

Wang et al. use several genome-wide approaches to investigate glucocorticoid receptor (GR) action in a podocyte cell line model. They conclude that direct GR bindings are enriched at super enhancers, highlighting a strategy potentially used by GR to regulate transcription through super-enhancers and...

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Autores principales:	Hong Wang, Aiping Duan, Jing Zhang, Qi Wang, Yuexian Xing, Zhaohui Qin, Zhihong Liu, Jingping Yang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/f5148a3c1b8044cdae070252e4de0c16
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spelling	oai:doaj.org-article:f5148a3c1b8044cdae070252e4de0c162021-12-02T15:02:48ZGlucocorticoid receptor wields chromatin interactions to tune transcription for cytoskeleton stabilization in podocytes10.1038/s42003-021-02209-82399-3642https://doaj.org/article/f5148a3c1b8044cdae070252e4de0c162021-06-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02209-8https://doaj.org/toc/2399-3642Wang et al. use several genome-wide approaches to investigate glucocorticoid receptor (GR) action in a podocyte cell line model. They conclude that direct GR bindings are enriched at super enhancers, highlighting a strategy potentially used by GR to regulate transcription through super-enhancers and long-range interactions.Hong WangAiping DuanJing ZhangQi WangYuexian XingZhaohui QinZhihong LiuJingping YangNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Hong Wang Aiping Duan Jing Zhang Qi Wang Yuexian Xing Zhaohui Qin Zhihong Liu Jingping Yang Glucocorticoid receptor wields chromatin interactions to tune transcription for cytoskeleton stabilization in podocytes
description	Wang et al. use several genome-wide approaches to investigate glucocorticoid receptor (GR) action in a podocyte cell line model. They conclude that direct GR bindings are enriched at super enhancers, highlighting a strategy potentially used by GR to regulate transcription through super-enhancers and long-range interactions.
format	article
author	Hong Wang Aiping Duan Jing Zhang Qi Wang Yuexian Xing Zhaohui Qin Zhihong Liu Jingping Yang
author_facet	Hong Wang Aiping Duan Jing Zhang Qi Wang Yuexian Xing Zhaohui Qin Zhihong Liu Jingping Yang
author_sort	Hong Wang
title	Glucocorticoid receptor wields chromatin interactions to tune transcription for cytoskeleton stabilization in podocytes
title_short	Glucocorticoid receptor wields chromatin interactions to tune transcription for cytoskeleton stabilization in podocytes
title_full	Glucocorticoid receptor wields chromatin interactions to tune transcription for cytoskeleton stabilization in podocytes
title_fullStr	Glucocorticoid receptor wields chromatin interactions to tune transcription for cytoskeleton stabilization in podocytes
title_full_unstemmed	Glucocorticoid receptor wields chromatin interactions to tune transcription for cytoskeleton stabilization in podocytes
title_sort	glucocorticoid receptor wields chromatin interactions to tune transcription for cytoskeleton stabilization in podocytes
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/f5148a3c1b8044cdae070252e4de0c16
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_version_	1718389114491895808

Glucocorticoid receptor wields chromatin interactions to tune transcription for cytoskeleton stabilization in podocytes

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