Glucocorticoid receptor wields chromatin interactions to tune transcription for cytoskeleton stabilization in podocytes
Wang et al. use several genome-wide approaches to investigate glucocorticoid receptor (GR) action in a podocyte cell line model. They conclude that direct GR bindings are enriched at super enhancers, highlighting a strategy potentially used by GR to regulate transcription through super-enhancers and...
Guardado en:
Autores principales: | Hong Wang, Aiping Duan, Jing Zhang, Qi Wang, Yuexian Xing, Zhaohui Qin, Zhihong Liu, Jingping Yang |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/f5148a3c1b8044cdae070252e4de0c16 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Glucocorticoid therapy regulates podocyte motility by inhibition of Rac1
por: James C. McCaffrey, et al.
Publicado: (2017) -
FAM40A alters the cytoskeleton of podocytes in familial focal and segmental glomerulosclerosis by regulating F-actin and nephrin
por: Zhou Chen, et al.
Publicado: (2018) -
Myo1e impairment results in actin reorganization, podocyte dysfunction, and proteinuria in zebrafish and cultured podocytes.
por: Jianhua Mao, et al.
Publicado: (2013) -
Cell health and cytoskeleton
Publicado: (2009) -
R-loop resolution promotes co-transcriptional chromatin silencing
por: Congyao Xu, et al.
Publicado: (2021)