Cell wall N-glycan of Candida albicans ameliorates early hyper- and late hypo-immunoreactivity in sepsis

Cell wall N-glycan of Candida albicans ameliorates early hyper- and late hypo-immunoreactivity in sepsis

Kawakita et al use a murine sepsis model to show that N-glycan from pathogenic C. albicans ameliorates sepsis - and thus improves survival - through upregulation of the cytokine IL-10. This study demonstrates a potential strategy in which the immunosuppressive mechanism of one pathogen can be applie...

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Bibliographic Details
Main Authors: Masataka Kawakita, Taiki Oyama, Ikuma Shirai, Shuto Tanaka, Kotaro Akaki, Shinya Abe, Takuma Asahi, Guangwei Cui, Fumie Itoh, Masato Sasaki, Nobuyuki Shibata, Koichi Ikuta, Tomomitsu Hatakeyama, Kazuhiko Takahara
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Biology (General)
QH301-705.5
Online Access:https://doaj.org/article/f517422173d447fa8da01bb742db42d0
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https://doaj.org/article/f517422173d447fa8da01bb742db42d0

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