The role of Leu260Phe polymorphism of the receptor gene to GLP-1 incretin in the pathogenesis of diabetes type 2 diabetes with obesity

BACKGROUND: Glucagon-like peptide-1 (GLP-1) stimulates the proliferation of β-cells, enhances their resistance to apoptosis and increases glucose-dependent insulin secretion. AIMS: Study of the relationship of Leu260Phe polymorphism (rs1042044) of the GLP-1R gene with postprandial hormone...

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Auteurs principaux: Daria A. Skuratovskaia, Maria A. Vulf, Elena V. Kirienkova, Natalia I. Myronyuk, Pavel A. Zatolokin, Larisa S. Litvinova
Format: article
Langue:EN
RU
Publié: Endocrinology Research Centre 2019
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Accès en ligne:https://doaj.org/article/f520af947a3b4dd080631b786275ae63
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