Benchmarking pipelines for subclonal deconvolution of bulk tumour sequencing data

Subclonal deconvolution in cancer sequencing data is a complex task, and the optimal tools to use are unclear. Here, the authors systematically benchmark subclonal deconvolution pipelines with a comprehensive set of simulated tumour genomes and identify the best-performing methods.

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Autores principales: Georgette Tanner, David R. Westhead, Alastair Droop, Lucy F. Stead
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/f5475b13ac43401197d2270caf88aa9a
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