The Ca2+ permeation mechanism of the ryanodine receptor revealed by a multi-site ion model

Although the permeation mechanisms for K+ and Na+ channels have been extensively studied, the ion permeation mechanism through Ca2+ channels was largely unknown. Here the authors develop a multisite Ca2+ model that can be used in the framework of classical MD simulations to study Ca2+ in a quantitat...

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Bibliographic Details
Main Authors: Aihua Zhang, Hua Yu, Chunhong Liu, Chen Song
Format: article
Language:EN
Published: Nature Portfolio 2020
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Online Access:https://doaj.org/article/f55196e6cf0f477e937e78a85ea0e7bb
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