A MicroRNA Network Controls <italic toggle="yes">Legionella pneumophila</italic> Replication in Human Macrophages via LGALS8 and MX1

A MicroRNA Network Controls <italic toggle="yes">Legionella pneumophila</italic> Replication in Human Macrophages via LGALS8 and MX1

ABSTRACT Legionella pneumophila is an important cause of pneumonia. It invades alveolar macrophages and manipulates the immune response by interfering with signaling pathways and gene transcription to support its own replication. MicroRNAs (miRNAs) are critical posttranscriptional regulators of gene...

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Bibliographic Details
Main Authors: Christina E. Herkt, Brian E. Caffrey, Kristin Surmann, Sascha Blankenburg, Manuela Gesell Salazar, Anna L. Jung, Stefanie M. Herbel, Kerstin Hoffmann, Leon N. Schulte, Wei Chen, Alexandra Sittka-Stark, Uwe Völker, Martin Vingron, Annalisa Marsico, Wilhelm Bertrams, Bernd Schmeck
Format: article
Language:EN
Published: American Society for Microbiology 2020
Subjects:
miRNA
infection
macrophage
MX1
bacteria
galectin-8
Microbiology
QR1-502
Online Access:https://doaj.org/article/f562f453df8b4591a2a3cac252c1f3ca
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