Viral regulation of host cell biology by hijacking of the nucleolar DNA-damage response

Viral regulation of host cell biology by hijacking of the nucleolar DNA-damage response

Many RNA viruses that replicate in the cytoplasm express proteins that localize to nucleoli, but the nucleolar functions remain largely unknown. Here, the authors show that the Henipavirus matrix protein mimics an endogenous Treacle partner of the DNA-damage response, resulting in suppression of rRN...

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Autores principales: Stephen M. Rawlinson, Tianyue Zhao, Ashley M. Rozario, Christina L. Rootes, Paul J. McMillan, Anthony W. Purcell, Amanda Woon, Glenn A. Marsh, Kim G. Lieu, Lin-Fa Wang, Hans J. Netter, Toby D. M. Bell, Cameron R. Stewart, Gregory W. Moseley
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Science
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Acceso en línea:https://doaj.org/article/f56415c38df4400f9a9e20a5ceee7848
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https://doaj.org/article/f56415c38df4400f9a9e20a5ceee7848

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