Maternal vaccination and protective immunity against Zika virus vertical transmission

A Zika virus vaccine should protect the fetus during pregnancy. Here, using a live-attenuated Zika vaccine, the authors show that a higher neutralizing antibody titer is required to protect from in utero transmission than to protect non-pregnant mice and that a single maternal immunization protects...

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Autores principales: Chao Shan, Xuping Xie, Huanle Luo, Antonio E. Muruato, Yang Liu, Maki Wakamiya, Jun-Ho La, Jin Mo Chung, Scott C. Weaver, Tian Wang, Pei-Yong Shi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/f5695ee8d606486d80040a70ba0f34f0
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