Spontaneous and frequent conformational dynamics induced by A…A mismatch in d(CAA)·d(TAG) duplex
Abstract Base pair mismatches in DNA can erroneously be incorporated during replication, recombination, etc. Here, the influence of A…A mismatch in the context of 5′CAA·5′TAG sequence is explored using molecular dynamics (MD) simulation, umbrella sampling MD, circular dichroism (CD), microscale ther...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2021
|
| Subjects: | |
| Online Access: | https://doaj.org/article/f56e1711fedf49b7ba866dfbf635bfb5 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|