High-throughput screening for growth inhibitors using a yeast model of familial paraganglioma.
Classical tumor suppressor genes block neoplasia by regulating cell growth and death. A remarkable puzzle is therefore presented by familial paraganglioma (PGL), a neuroendocrine cancer where the tumor suppressor genes encode subunits of succinate dehydrogenase (SDH), an enzyme of the tricarboxylic...
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Autores principales: | , , , , , , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
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Public Library of Science (PLoS)
2013
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Materias: | |
Acceso en línea: | https://doaj.org/article/f59d566d9d2d4a60a0109f1d98d39a5c |
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