Reconstruction and topological characterization of the sigma factor regulatory network of Mycobacterium tuberculosis

Sigma factors are regulatory proteins that reprogram the bacterial RNA polymerase in response to stress conditions to transcribe certain genes, including those for other sigma factors. Here, Chauhan et al. describe the complete sigma factor regulatory network of the pathogen Mycobacterium tuberculos...

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Autores principales:	Rinki Chauhan, Janani Ravi, Pratik Datta, Tianlong Chen, Dirk Schnappinger, Kevin E. Bassler, Gábor Balázsi, Maria Laura Gennaro
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f5a0a34f52fb459c82e9b951c157c028
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spelling	oai:doaj.org-article:f5a0a34f52fb459c82e9b951c157c0282021-12-02T17:33:09ZReconstruction and topological characterization of the sigma factor regulatory network of Mycobacterium tuberculosis10.1038/ncomms110622041-1723https://doaj.org/article/f5a0a34f52fb459c82e9b951c157c0282016-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms11062https://doaj.org/toc/2041-1723Sigma factors are regulatory proteins that reprogram the bacterial RNA polymerase in response to stress conditions to transcribe certain genes, including those for other sigma factors. Here, Chauhan et al. describe the complete sigma factor regulatory network of the pathogen Mycobacterium tuberculosis.Rinki ChauhanJanani RaviPratik DattaTianlong ChenDirk SchnappingerKevin E. BasslerGábor BalázsiMaria Laura GennaroNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Rinki Chauhan Janani Ravi Pratik Datta Tianlong Chen Dirk Schnappinger Kevin E. Bassler Gábor Balázsi Maria Laura Gennaro Reconstruction and topological characterization of the sigma factor regulatory network of Mycobacterium tuberculosis
description	Sigma factors are regulatory proteins that reprogram the bacterial RNA polymerase in response to stress conditions to transcribe certain genes, including those for other sigma factors. Here, Chauhan et al. describe the complete sigma factor regulatory network of the pathogen Mycobacterium tuberculosis.
format	article
author	Rinki Chauhan Janani Ravi Pratik Datta Tianlong Chen Dirk Schnappinger Kevin E. Bassler Gábor Balázsi Maria Laura Gennaro
author_facet	Rinki Chauhan Janani Ravi Pratik Datta Tianlong Chen Dirk Schnappinger Kevin E. Bassler Gábor Balázsi Maria Laura Gennaro
author_sort	Rinki Chauhan
title	Reconstruction and topological characterization of the sigma factor regulatory network of Mycobacterium tuberculosis
title_short	Reconstruction and topological characterization of the sigma factor regulatory network of Mycobacterium tuberculosis
title_full	Reconstruction and topological characterization of the sigma factor regulatory network of Mycobacterium tuberculosis
title_fullStr	Reconstruction and topological characterization of the sigma factor regulatory network of Mycobacterium tuberculosis
title_full_unstemmed	Reconstruction and topological characterization of the sigma factor regulatory network of Mycobacterium tuberculosis
title_sort	reconstruction and topological characterization of the sigma factor regulatory network of mycobacterium tuberculosis
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/f5a0a34f52fb459c82e9b951c157c028
work_keys_str_mv	AT rinkichauhan reconstructionandtopologicalcharacterizationofthesigmafactorregulatorynetworkofmycobacteriumtuberculosis AT jananiravi reconstructionandtopologicalcharacterizationofthesigmafactorregulatorynetworkofmycobacteriumtuberculosis AT pratikdatta reconstructionandtopologicalcharacterizationofthesigmafactorregulatorynetworkofmycobacteriumtuberculosis AT tianlongchen reconstructionandtopologicalcharacterizationofthesigmafactorregulatorynetworkofmycobacteriumtuberculosis AT dirkschnappinger reconstructionandtopologicalcharacterizationofthesigmafactorregulatorynetworkofmycobacteriumtuberculosis AT kevinebassler reconstructionandtopologicalcharacterizationofthesigmafactorregulatorynetworkofmycobacteriumtuberculosis AT gaborbalazsi reconstructionandtopologicalcharacterizationofthesigmafactorregulatorynetworkofmycobacteriumtuberculosis AT marialauragennaro reconstructionandtopologicalcharacterizationofthesigmafactorregulatorynetworkofmycobacteriumtuberculosis
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Reconstruction and topological characterization of the sigma factor regulatory network of Mycobacterium tuberculosis

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