Designer cells programming quorum-sensing interference with microbes

Bacterial populations communicate with AI-2 signaling molecules, helping to coordinate biofilm development and other group behaviors. Here the authors design a genetic circuit for mammalian cells that allows them to sense bacterial populations and interfere with quorum communication.

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Autores principales: Ferdinand Sedlmayer, Dennis Hell, Marius Müller, David Ausländer, Martin Fussenegger
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/f5b4f3ce5f3b40af8b18e1f0b070f445
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spelling oai:doaj.org-article:f5b4f3ce5f3b40af8b18e1f0b070f4452021-12-02T15:33:38ZDesigner cells programming quorum-sensing interference with microbes10.1038/s41467-018-04223-72041-1723https://doaj.org/article/f5b4f3ce5f3b40af8b18e1f0b070f4452018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04223-7https://doaj.org/toc/2041-1723Bacterial populations communicate with AI-2 signaling molecules, helping to coordinate biofilm development and other group behaviors. Here the authors design a genetic circuit for mammalian cells that allows them to sense bacterial populations and interfere with quorum communication.Ferdinand SedlmayerDennis HellMarius MüllerDavid AusländerMartin FusseneggerNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Ferdinand Sedlmayer
Dennis Hell
Marius Müller
David Ausländer
Martin Fussenegger
Designer cells programming quorum-sensing interference with microbes
description Bacterial populations communicate with AI-2 signaling molecules, helping to coordinate biofilm development and other group behaviors. Here the authors design a genetic circuit for mammalian cells that allows them to sense bacterial populations and interfere with quorum communication.
format article
author Ferdinand Sedlmayer
Dennis Hell
Marius Müller
David Ausländer
Martin Fussenegger
author_facet Ferdinand Sedlmayer
Dennis Hell
Marius Müller
David Ausländer
Martin Fussenegger
author_sort Ferdinand Sedlmayer
title Designer cells programming quorum-sensing interference with microbes
title_short Designer cells programming quorum-sensing interference with microbes
title_full Designer cells programming quorum-sensing interference with microbes
title_fullStr Designer cells programming quorum-sensing interference with microbes
title_full_unstemmed Designer cells programming quorum-sensing interference with microbes
title_sort designer cells programming quorum-sensing interference with microbes
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/f5b4f3ce5f3b40af8b18e1f0b070f445
work_keys_str_mv AT ferdinandsedlmayer designercellsprogrammingquorumsensinginterferencewithmicrobes
AT dennishell designercellsprogrammingquorumsensinginterferencewithmicrobes
AT mariusmuller designercellsprogrammingquorumsensinginterferencewithmicrobes
AT davidauslander designercellsprogrammingquorumsensinginterferencewithmicrobes
AT martinfussenegger designercellsprogrammingquorumsensinginterferencewithmicrobes
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