Designer cells programming quorum-sensing interference with microbes
Bacterial populations communicate with AI-2 signaling molecules, helping to coordinate biofilm development and other group behaviors. Here the authors design a genetic circuit for mammalian cells that allows them to sense bacterial populations and interfere with quorum communication.
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Nature Portfolio
2018
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oai:doaj.org-article:f5b4f3ce5f3b40af8b18e1f0b070f4452021-12-02T15:33:38ZDesigner cells programming quorum-sensing interference with microbes10.1038/s41467-018-04223-72041-1723https://doaj.org/article/f5b4f3ce5f3b40af8b18e1f0b070f4452018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04223-7https://doaj.org/toc/2041-1723Bacterial populations communicate with AI-2 signaling molecules, helping to coordinate biofilm development and other group behaviors. Here the authors design a genetic circuit for mammalian cells that allows them to sense bacterial populations and interfere with quorum communication.Ferdinand SedlmayerDennis HellMarius MüllerDavid AusländerMartin FusseneggerNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018) |
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DOAJ |
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DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q Ferdinand Sedlmayer Dennis Hell Marius Müller David Ausländer Martin Fussenegger Designer cells programming quorum-sensing interference with microbes |
description |
Bacterial populations communicate with AI-2 signaling molecules, helping to coordinate biofilm development and other group behaviors. Here the authors design a genetic circuit for mammalian cells that allows them to sense bacterial populations and interfere with quorum communication. |
format |
article |
author |
Ferdinand Sedlmayer Dennis Hell Marius Müller David Ausländer Martin Fussenegger |
author_facet |
Ferdinand Sedlmayer Dennis Hell Marius Müller David Ausländer Martin Fussenegger |
author_sort |
Ferdinand Sedlmayer |
title |
Designer cells programming quorum-sensing interference with microbes |
title_short |
Designer cells programming quorum-sensing interference with microbes |
title_full |
Designer cells programming quorum-sensing interference with microbes |
title_fullStr |
Designer cells programming quorum-sensing interference with microbes |
title_full_unstemmed |
Designer cells programming quorum-sensing interference with microbes |
title_sort |
designer cells programming quorum-sensing interference with microbes |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/f5b4f3ce5f3b40af8b18e1f0b070f445 |
work_keys_str_mv |
AT ferdinandsedlmayer designercellsprogrammingquorumsensinginterferencewithmicrobes AT dennishell designercellsprogrammingquorumsensinginterferencewithmicrobes AT mariusmuller designercellsprogrammingquorumsensinginterferencewithmicrobes AT davidauslander designercellsprogrammingquorumsensinginterferencewithmicrobes AT martinfussenegger designercellsprogrammingquorumsensinginterferencewithmicrobes |
_version_ |
1718387060478312448 |