Designer cells programming quorum-sensing interference with microbes
Bacterial populations communicate with AI-2 signaling molecules, helping to coordinate biofilm development and other group behaviors. Here the authors design a genetic circuit for mammalian cells that allows them to sense bacterial populations and interfere with quorum communication.
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Main Authors: | Ferdinand Sedlmayer, Dennis Hell, Marius Müller, David Ausländer, Martin Fussenegger |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2018
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Subjects: | |
Online Access: | https://doaj.org/article/f5b4f3ce5f3b40af8b18e1f0b070f445 |
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