Designer cells programming quorum-sensing interference with microbes

Bacterial populations communicate with AI-2 signaling molecules, helping to coordinate biofilm development and other group behaviors. Here the authors design a genetic circuit for mammalian cells that allows them to sense bacterial populations and interfere with quorum communication.

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Bibliographic Details
Main Authors: Ferdinand Sedlmayer, Dennis Hell, Marius Müller, David Ausländer, Martin Fussenegger
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
Q
Online Access:https://doaj.org/article/f5b4f3ce5f3b40af8b18e1f0b070f445
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