Chondroitin 6-sulfate represses keratinocyte proliferation in mouse skin, which is associated with psoriasis
Kitazawa et al. show that chondroitin 6-sulfate represses keratinocyte proliferation in skin. They find that mice deficient in chondroitin-6-O-sulfotransferase-1 (C6st-1), which synthesizes chondroitin 6-sulfate, exhibit keratinocyte hyperproliferation and impaired skin permeability barrier. This st...
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Format: | article |
Langue: | EN |
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Nature Portfolio
2021
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Accès en ligne: | https://doaj.org/article/f5ee692e9c0645bdbe1c36a9b082fc46 |
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