MYCN contributes to the sensitization of acute myelogenous leukemia cells to cisplatin by targeting SRY-box transcription factor 4

Little was known about the role of MYCN in drug resistance in acute myeloid leukemia (AML). We investigated impacts of MYCN on sensitization of AML cell to cisplatin, and its interaction with SRY-box transcription factor 4 (SOX4). In vitro, human AML cell lines HL60 and KG-1 were transfected with th...

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Bibliographic Details
Main Authors: Xianbao Huang, Ling Qi, Wei Lu, Ziye Li, Wuping Li, Fei Li
Format: article
Language:EN
Published: Taylor & Francis Group 2021
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Online Access:https://doaj.org/article/f5f9fcbfe37a41d894aea6a42f012166
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