Saturated fatty acids modulate cell response to DNA damage: implication for their role in tumorigenesis.
DNA damage triggers a network of signaling events that leads to cell cycle arrest or apoptosis. This DNA damage response acts as a mechanism to prevent cancer development. It has been reported that fatty acids (FAs) synthesis is increased in many human tumors while inhibition of fatty acid synthase...
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Auteurs principaux: | Li Zeng, Guang-Zhi Wu, Kim Jee Goh, Yew Mun Lee, Chuo Chung Ng, Ang Ben You, Jianhe Wang, Deyong Jia, Aijun Hao, Qiang Yu, Baojie Li |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2008
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Accès en ligne: | https://doaj.org/article/f61b9e16b56d43aba5b5ddd2df35e5b1 |
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